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蒋 涛博士,讲师


E-mail: jiangtao@htu.edu.cn

教育与工作 经历:

2014.04-至今betway官方app ,化学化工学院,教师

2008.9-2013.6武汉大学化学与分子科学学院,获理学博士学位

2004.9-2008.6betway官方app 化学与环境科学学院,获理学学士学位

主讲课程:

《药剂学》,《药剂学实验》,《工程伦理》

研究领域与兴趣:

纳米材料的设计合成、药物传递系统

年来主持的主要科研项目:

  1. 河南省高等学校重点科研项目:生物可降解聚碳酸酯前药载体的设计、合成及性能研究,项目编号:15A1500532015.01-2016.122万元

  2. 新乡市科技攻关项目:生物可降解聚碳酸酯在改善紫杉醇类药物水溶性中的应用,项目编号:ZG150052014.01-2016.125万元

  3. betway官方app 国家级科研项目培育基金:聚碳酸酯前药的设计、合成及靶向性能研究,项目编号:201800852017.1-2019.126万元

  4. betway官方app 青年科学基金项目:基于生物可降解聚碳酸酯前药载体的合成及靶向性能研究,项目编号:201801462015.1-2017.123万元

代表性论文与专利:

  1. Yanwei Chi, Zhiying Wang, Jie Wang, Wenpei Dong, Pengyang Xin, Jingjing Bi,Tao Jiang*, Chang-Po Chen*, Dimeric camptothecin-loaded mPEG-PCL nanoparticles with high drug loading and reduction-responsive drug release. Coloid and Polyer Science,2020, 298, 51–58.

  2. Tao Jiang, Xin Wang, Ge Wang, Yafu Wang, Kui Wang, Xiaopeng Xuan, Changpo Chen*, Kai Jiang, Hua Zhang*. Light-activated cycle-reversible intramolecular charge transfer fluorescent probe: monitoring of pHi trace change induced by UV light in programmed cell death, Chem. Commun.2019, 55,5279-5282.

  3. Pengyang Xin*, Huiyuan Kong, Yonghui Sun, Lingyu Zhao, Haodong Fang, ,Haofeng Zhu,Tao Jiang, Jingjing Guo, Qian Zhang, Wenpei Dong, Chang-Po Chen* Artificial K+ Channels Formed by Pillararene-Cyclodextrin Hybrid Molecules: , Tuning Cation Selectivity and Generating Membrane Potential.Angewandte Chemie International Edition. 2019, 58(9): 2779-2784.

  4. Pengyang Xin,* Yonghui Sun, Huiyuan Kong, Yaodong Wang, Si Tan, Jingjing Guo,Tao Jiang, Wenpei Dong,* Chang-Po Chen*. A unimolecular channel fromed by dual helical peptide modified pillar[5]arene: correlating transmembrane transport properties with antimicrobial activity and haemolytic toxicityChem. Comm.2017, 53, 11492-11495

  5. Pengyang Xin,* Si Tan, Yonghui Sun, Qiaojv Ren,Wenpei Dong, Jingjing Guo,Tao Jiangand Chang-Po Chen*One-pot formation of hydrazide macrocycles with modified cavities: an example of pH-sensitive unimolecular cation channelsChem. Comm.2017, 52, 5322-5325.

  6. Hua Zhang*, Caixia Wang , Tao Jiang , Haiming Guo* , Ge Wang , Xinhua Cai , Lin Yang , Yi Zhang , Haichuan Yu , Hui Wang , and Kai Jiang .Microtubule-Targetable Fluorescent Probe: Site-Specific Detection and Super-Resolution Imaging of Ultratrace Tubulin in Microtubules of Living Cancer Cells.Analytical Chemistry.2015, 87, 5216-5222.

  7. Hua Zhang*,Jiangli Fan,Kui Wang,Jing Li,Caixia Wang,Yamin Nie,Tao Jiang, Huiying Mu,Xiaojun Peng,and Kai Jiang.Highly Sensitive Naphthalene-Based Two-Photon Fluorescent Probefor in Situ Real-Time Bioimaging of Ultratrace Cyclooxygenase‑2 inLiving Biosystems.Analytical Chemistry.2014, 86, 9131-9138.

  8. Tao Jiang,Feng He, Renxi Zhuo. Synthesis,characterization and enzymatic degradation of novel biodegradable copolymers of5-allyloxy-1,3-dioxan-2-one withε-caprolactone. Polymer Degradation andStability. 2013, 98(1), 325-330.

  9. Tao Jiang, Youmei Li, Yin Lv, YinjiaCheng, Feng He and Renxi Zhuo. Amphiphilic polycarbonate conjugates ofdoxorubicin with pH-sensitive hydrazone linker for controlled release. Colloidsand Surfaces B: Biointerfaces. 2013, 111, 542-548.

  10. Tao Jiang, Youmei Li, Yin Lv, YinjiaCheng, Feng He, Renxi Zhuo Amphiphilic Block-Graft copolymers based onPoly(ethylene glycol)-b-(polycarbonates-g-polycarbonates) for Controlled Releaseof Doxorubicin. Journal of Materials Science-Materials in Medicine 2014, 25, 131-139.

  11. 郑晓明,蒋涛,贺枫. PNIPAM-b-聚碳酸酯温敏胶束的制备及用作药物控制释放载体的研究.高分子学报,2011,8, 895-902

  12. Feng He*, Changfang Wang,Tao Jiang,Bing Han, Renxi Zhuo. Poly[(5-methyl-5-allyloxycarbonyl-trimethylenecarbonate)-co-(5,5-dimethyl-trimethylenecarbonate)] with Grafted Polyethylenimine as Biodegradable Polycations forEfficient Gene Delivery. Biomacromolecules. 2010, 11, 3028-3035.

  13. Changfang Wang, Yanxin Lin,Tao Jiang, Feng He*, Renxi Zhuo.Polyethylenimine-grafted polycarbonates as biodegradable polycations for genedelivery. Biomaterials. 2009, 30, 4824-4832.

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