代表性论文: 1.Liu YX, Feng YB, Wang L, etal., Structural insights into phosphite dehydrogenase variants favoring a non-naturalredox cofactor. ACS Catal., 2019, 9(3), 1883-1887. 2.Liu YX; Guo XJ; Liu WJ, etal., Structural insights into malic enzyme variants favoring a non-naturalredox cofactor, ChemBioChem, 2021, 10.1002/cbic.2020008. 3.Liu YX; Li Q; Wang L, et al.,Engineering D-lactate dehydrogenase to favor a non-natural cofactor nicotinamide cytosine dinucleotide, ChemBioChem, 2020, 21(14), 1972-1975. 4. Guo XJ;Liu YX; Wang Q, etal., Non-natural cofactor and formate driven reductive carboxylation of pyruvate,Angew. Chem. Int. Ed., 2020, 59(8), 3143-3146. 5. Guo XJ; Wang XY;Liu YX, etal.,Structure-guided design of formate dehydrogenase for regeneration of a non-naturalredox cofactor, Chem. Eur. J., 2020, 26, 16611–16615. 6. Peng C,Liu YX, Guo XJ, et al.,Selective carboxylation of substituted phenols with engineeredEscherichia coliwhole-cells. Tetrahedron Lett., 2018, 59, 3810-3815.(共同一作) 7. Wang L, Liu B,Liu YX, et al.,An Escherichia coli strain designed for characterizing in vivo functions of nicotinamide adenine dinucleotide analogs. Org. Lett., 2019,21(3), 3218-3222. 8. Guo XJ, Shen HW,Liu YX, etal., Enabling heterologous synthesis of lupulones in the yeastSaccharomy cescerevisiae. Appl. Biochem. Biotechnol., 2019, 188, 787-797. 9. Wang L, Ji DB,Liu YX, et al.,Synthetic cofactor-linked metabolic circuits for selective energy transfer. ACSCatal., 2017, 7, 1977-1983. 专利成果: 1. 赵宗保, 刘玉雪, 王雪颖,等, 一种NAD类似物偏好型氧化还原酶的筛选方法. 专利申请号: 201711336831.6 2.赵宗保, 刘玉雪, 王雪颖, 一种生物催化还原丙酮酸产D-乳酸的方法. 专利申请号: 201910303767.4 3.赵宗保, 王雪颖, 刘玉雪. 酶促合成烟酰胺胞嘧啶二核苷酸的方法. 专利申请号: 201510940681.4 4.赵宗保, 王雪颖, 刘玉雪. 酶促合成烟酰胺尿嘧啶二核苷酸的方法. 专利申请号: 201510939556.1 5.赵宗保, 刘武军, 郭潇佳, 刘玉雪. 一种生物催化甘油产1, 3-丙二醇的方法. 专利申请号: 201811154814.5 |