仉晓文
发布时间:2022-03-11 15:50:20 浏览次数:6441





姓名: 仉晓文

职称: 教授(博导)

办公电话: 13949605978

电子邮箱: zxwhtu@163.com








个人简介:

2006年,山东大学动物科学专业本科毕业。2011年,山东大学动物学专业博士毕业,同年入职betway官方app 。主持完成了国家自然科学基金青年基金和面上项目,河南省自然科学基金,河南省基础与前沿项目,河南省科技攻关项目等。以第一作者或者通讯作者发表SCI论文17篇。

研究领域:

主要研究甲壳动物先天免疫系统,包括模式识别受体,抗菌肽及免疫信号通路,尤其是对模式识别受体C-型凝集素的研究有着丰富的理论知识与实验经历。

主要学术及社会兼职:

中国水产学会会员、中国动物学会会员、中国生化与分子生物学学会会员。

主持或参加科研项目情况:

主持:

1. 螯虾甘露糖受体抗白斑综合征病毒研究,编号31873047,国家自然科学基金面上项目,2019.01-2020.12。

2. 螯虾含免疫球蛋白结构域C-型凝集素的免疫功能研究, 编号31301883,国家自然科学基金青年基金项目,2014.01-2016.12。

3. 中华绒螯蟹C-型凝集素参与白斑综合征病毒感染的机制研究,编号162300410166,河南省自然科学基金项目。2017.01-2018.12。

4. 螯虾致病菌鞭毛蛋白受体的抗菌作用和渔药应用,编号212102110380,河南省科技攻关项目。2021.01-2022.12。

5. 螯虾甘露糖受体抗白斑综合征病毒研究,编号20180554,betway官方app 优秀青年科学基金2018.01-2020.12。

6. 螯虾中含免疫球蛋白结构域的C型凝集素抗病作用研究,编号132300410140,河南省基础与前沿技术研究计划项目,2013.01-2015.12。

7. 中华绒螯蟹模式识别受体参与病原防御的分子机制研究,编号12A180018,河南省教育厅科学技术研究重点项目,2012.01-2014.12。

参与:

1. 对虾抗病毒相关基因的功能与抗病毒机理分析,编号31130056,国家自然科学基金重点项目,2012.01-2016.12,参与。

生物乙醇生产菌株改良研究,编号082102220012,河南省科技厅,2008.01-2010.12,参与。

学术成果:

代表性论文:

(1) Zhang XW, Han KK, Yang CH, Xia XH, Ren Q, Zhang HW. Astomach-specific lectin plays a crucial role in the innate immunity of redswamp crayfish,Procambarus clarkia. Fish & Shellfish Immunology.103:285-292(2020).

(2) Zhang XW, Yang CH, Xia XH, Pan XT, Jin ZY, Yu H, Zhang HW. Atriple WAP domain containing protein acts in antibacterial immunity of weatherloach,Misgurnus anguillicaudatus. Fish & Shellfish Immunology.103,277-284 (2020).

(3) Zhang XW, Yang CH, Zhang HQ, Pan XT, Jin ZY, Zhang HW, XiaXH. A C-type lectin with antibacterial activity in weather loach,Misgurnus anguillicaudatus. Journal of Fish Diseases. (2020).

(4) Zhang XW*,Wang Y, Wang XW, Wang L, Mu Y, Wang JX*.A C-type lectin with an immunoglobulin-like domain promotes phagocytosis of hemocytes in crayfishProcambarus clarkii.Scientific Reports. 6, 29924. (2016).

(5) Zhang XW,Wang XW,Huang Y,Hui KM,Shi YR,Wang W*, Ren Q*. Cloning and characterization of two different ficolins from the giant freshwater prawnMacrobrachium rosenbergii.Developmentaland Comparative Immunology. 44(2), 359-69 (2014).

(6) Zhang XW,Xu WT, Wang XW, Mu Y, Zhao XF, Yu XQ, Wang JX. A novel C-type lectin with twoCRD domains from Chinese shrimpFenneropenaeus chinensisfunctions as a pattern recognition protein. Molecular Immunology.46(8-9), 1626-37 (2009).

(7) Zhang XW,Wang XW, Sun C, Zhao XF, Wang JX. C-type lectin (Pc-Lec1) from freshwater crayfishProcambarus clarkiiand itsfunction in hemocyte encapsulation. Archivesof Insect Biochemistry and Physiology 76 (3), 168-84 (2011).

(8) Pan XT, Li TT, Yang CH, Ren Q, Zhang XW*.A toll receptor is involved in antibacterial defense in the oriental riverprawn,Macrobrachium nipponense. Fish & Shellfish Immunology.92, 583-589 (2019).

(9) Zhang XW,Man X, Huang X, Wang Y, Song QS, Hui KM*,Zhang HW*. Identification of a C-type lectin possessing both antibacterial and antiviral activities from redswamp crayfish. Fish & Shellfish Immunology.77, 22-30 (2018).

(10) Li TT, Ding ZF, Pan XT, Ma FT, Han KK, Wu L, Zhao LL, Ren Q∗, Zhang XW*. Characterization of an immune deficiency (IMD) homologfrom the oriental river prawn,Macrobrachium nipponense. Fish & Shellfish Immunology.83, 115-122 (2018).

(11) Man X, Pan XT, Zhang HW, Wang Y, Li XC*,Zhang XW*. A mannose receptor is involved in the anti-Vibrio defense of redswamp crayfish. Fish & Shellfish Immunology.82, 258-266 (2018).

(12) Wang Y, Zhang C, Wang H, Ma H, Huang YQ, Lu JX, Li XC*, Zhang XW*.Involvement of a newly identified atypical type IIcrustin (SpCrus5) in the antibacterial immunity of mud crabScylla paramamosain. Fish & Shellfish Immunology.75, 346-356 (2018).

(13) Zhang HW, Man X, Wang Y, Song QS, Stanley D, Hui KM*, Zhang XW*. Characterization of a double WAP domain-containing protein from the red swamp crayfishProcambarus clarkia. Fish & Shellfish Immunology. 71,329-337(2017).

(14) Zhang HW, Huang Y, Man X, Wang Y, Hui KM*,Yin SW*, Zhang XW*. HcToll3 was involved in anti-Vibrio defense in freshwater pearl mussel,Hyriopsis cumingii. Fish & Shellfish Immunology.63, 189-95 (2017).

(15) Zhang XW,Ren Q,Zhang HW,Wang KK,Wang JX.A C-type lectin could selectively facilitate bacteria clearance in red swamp crayfish,Procambarus clarkii. Fish Shellfish Immunol 35(5), 1387-94 (2013).

(16) Zhang XW, Liu YY, Mu Y, Ren Q, Zhao XF, Wang JX.Over expression of a C-type lectin enhances bacterial resistance in red swamp crayfishProcambarus clarkii. Fish Shellfish Immunol 34(5), 1112-8 (2013).

(17) Li XC, Zhang XW, Zhou JF,Ma HY,Liu ZD,Zhu L,Yao XJ,Li LG,Fang WH.Identification, characterization, and functional analysis of tube and pelle homologs in the mud crabScylla paramamosain. PLoS One 8(10),(2013).(并列第一作者)

18.仉晓文,夏晓华,王可可,彭方林,王林嵩。鳌虾血细胞中一种新的astakine样造血因子的克隆及表达.中国生物化学与分子生物学报(核心期刊二级学报)2013, 29 (12),1172-1179.







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