代表性论文: 1. Chang CF, Wang DL,Xi LL, Guo XQ, Wang G,P Yu GY. The orphan GPR50 receptor interacting with TβRIinduces G1/S-phase cell cycle arrest via Smad3-p27/p21 in BRL-3A cells. BiochemPharmacol. 2022, 202:115117.
2.Chang CF, Xie JJ, Yang QD, Yang J, Luo YR, Xi LL, Guo JL, Yang GG, Jin W, Wang GP. Serine peptidase inhibitor Kazal type III (SPINK3) promotes BRL‐3A cell proliferation by targeting the PI3K–AKT signaling pathway. Journal of Cellular Physiology. 2020, 235(3): 2209-2219.
3.Li JJ, Ye CL, Chang CF. Comparative transcriptomics analysis revealing flower trichome development during flower development in two Lonicera japonica Thunb. cultivars using RNA-seq. BMC Plant Biol. 2020, 20(1):341. 4.Wang GP, Chu PP, Chen M, Cheng LY, Zhao CC, Chen SS, Li XF, Yang GG, Chang CF. Osteopontin promotes rat hepatocyte proliferation both in vitro and in vivo. Artificial Cells, Nanomedicine and Biotechnology. 2019, 47(1): 3745-3757. 5.Wang GP; Guo XQ, Cheng LY, Chu PP, Chen M, Chen YH, Chang CF. An integrated analysis of the circRNA-miRNA-mRNA network reveals novel insights into pot ential mechanisms of cell proliferation during liver regeneration, Artificial Cells, Nanomedicine and Biotechnology. 2019, 47(1): 3873-3884. 6.Chang CF, Zhao WM, Luo YR, Xi LL, Chen SS, Zhao CC, Wang GP, Guo JL, Xu CS. Serine peptidase inhibitor Kazal type I (SPINK1) promotes BRL-3A cell proliferation via p38, ERK,and JNK pathways. Cell Biochem Funct. 2017, 35(6):339-348. 7.Chang CF, Niu ZP, Gu NN, Zhao WM, Wang GP, Jia YF, Li DM, Xu CS. Analysis of the ways and methods of signaling pathways in regulating cell cycle of NIH3T3 at transcriptional level. BMC Cell Biology, 2015, 16:25. 8.Chang CF, Xu CS. Transcriptome atlas of aromatic amino acid family metabolism-related genes in eight liver cell types uncovers the corresponding metabolic pathways in rat liver regeneration. Int J Biochem Cell Biol, 2010, 42(10):1708-1716. 9.Xu CS, Chang CF. Expression profiles of the genes associated with metabolism and transport of amino acids and their derivatives in rat liver regeneration. Amino Acids. 2008, 34(1):91-102. 10.Chang CF, Yang J, Li XF, Zhao WM, Li Y, Guo PJ, Wang GP, Xu CS. Thrombopoietin signaling pathway regulates the hepatocytes activation in rat liver regeneration. Biochem Genet, 2015, 53(9-10): 244-259. 11.Chang CF, Yang J, Li XF, Zhao WM, Chen SS, Wang GP, Xu CS. SPINK3: A novel growth factor that promotes rat liver regeneration. Molecular Biology, 2016, 50(3):398-404. 12.Chang CF, Zhao WM, Yang J, Li MH, Zhou Y, Xu CS. Study on activity of the signaling pathways regulating hepatocyte differentiation during rat liver regeneration. Anim Cells Syst, 2014, 18(6): 416-424. 13.Chang CF, Xu CS. Transcriptome atlas of glutamine family amino acid metabolism-related genes in eight regenerating liver cell types. Cell Biol Int, 2010, 34(12):1189-1198. 14.Chang CF, Fan JY, Zhang FC, Ma J, Xu CS. Transcriptome atlas of eight liver cell types uncovers effects of histidine catabolites on rat liver regeneration. J Genet, 2010, 89(4):425-436. 15.Chang CF, Yang J, Zhao WM, Li Y, Guo PJ, Li MH, Zhou Y, Xu CS. Gene expression profiling analysis of 5-hydroxytryptamine signaling pathway in rat regenerating liver and different types of liver cells. Genet Mol Res, 2015, 14(2): 3409-3420. 16.Chang CF, Zhao WM, Mei JX, Zhou Y, Pan CY, Xu TT, Xu CS. Branches of NF-κb signaling pathway regulate hepatocyte proliferation in rat liver regeneration. Genet Mol Res, 2015,14 (3):7643-7654. 17.Geng XF, Chang CF, Zang XY, Sun JY, Li PF, Guo JL, Xu CS. Integrative proteomic and microRNA analysis of the priming phase during rat liver regeneration. Gene, 2016, 575(2 Pt 1):224-232. 18.Ding Y, Chang CF, Niu ZP, Dai KQ, Geng XF, Li DM, Guo JL, Xu CS. Overexpression of Transcription Factor Foxa2 and Hnf1α induced Rat Bone Mesenchymal Stem Cells into Hepatocyte. Cytotechnology, 2016, 68(5):2037-2047. 专利成果: 1.基于OPN基因诱导的肝细胞体外增殖方法(专利号: ZL201510773582.1) 2.一种表达人血清白蛋白的质粒和重组菌以及它们的应用(ZL 201310078906.0) 3.表达人血清白蛋白的质粒和重组菌以及它们的应用(ZL 201310078280.3) 4 一种抗癌药物及其应用(ZL 2018 10968867.4) |